Year 1 – Introduction to Neuroscience: Neurons, sensory organs, and the brain
Motivation: Our curriculum this year relies heavily on inputs from monastics involved in the ETSI, to build basic understandings of neuroscience and conceptual bridges to monastics’ Buddhist studies and practices. A driving motivation for the year’s curriculum draws from the mutual scientific and Buddhist concern with this question: What is sentience? Individual pedagogical sessions each are guided by their own related questions.
Curriculum
- Big Questions: What is the nervous system made of? What are the principles on which nervous system activity is based?
- Lectures
- What do organisms need to know about the world?
- Activities
- Introduction of the teaching team, assign student working groups
- Understanding the Brain and Mind: Perspectives from Buddhism and from Neuroscience
- What is sentience?
- Big Questions: How do western scientists study the human brain, mind, and behavior? What can neuroscience teach us? What are its limitations?
- Lectures
- Overview of neuroscience, a multidisciplinary field
- Modes of inquiry
- Activity
- Scientific method
- Graphing exercise
- Big Questions: What does the brain do and how does it work? How does the brain organize the huge streams of incoming information? Is consciousness an emergent property?
- Lectures
- Overview of the human brain
- Central and peripheral nervous systems
- Activity
- Building brains
- Big Questions: How is the system organized to gather, transmit, and process information, then act on it? How do we convert physical energies into subjective experiences? What are the rules for organizing this information?
- Lectures
- What are nervous systems made of?
- Components and connections
- Activities
- Mid-course review
- Vocabulary quiz
- Big Questions: What is the neural basis for processing information? How do we learn? What guides our behaviors and actions?
- Lecture
- Neural connections
- Activity
- Brain charades
- Big Questions: Why do brains and nervous systems of creatures differ? What can this tell us about organic design or about the human brain?
- Lecture
- Brain evolution, comparative anatomy
- Activity
- Form and function
- Recap of Big Questions
- Final review, question and answer session
- Review session
- Study time
- Final exam
- Exam results, overall score, awards
- Closing party
Year 2 – The science of knowing, understanding, and behaving
Motivation: This year’s curriculum is motivated by the question of “How do we know?” How do we as living beings perceive and experience our worlds? But also, how do neuroscientists gain knowledge and understanding?
We use the visual system as an exemplar for how information is captured and processed.
Curriculum
- Big Questions: How has understanding of sentience and the brain developed in western science? Why is neuroscience so new, compared to physics or biology?
- Lectures
- Introduction to neuroscience
- How do we know? Information acquisition and analysis
- Sensory systems; Vision as a model
- Activities
- Introduction of the teaching team, assign student working groups
- Re/training in use of clickers
- Discussion: Weighing the evidence
- Big Questions: What do the nervous system do? Why have a brain?
- Lectures
- Overview of anatomy
- Organization of the nervous system
- Navigating the brain: Terms for orientation
- Activities
- Demo: Night vision goggles
- Computer lab: Functional Neuroanatomy and Brain Tutor
- Big Questions: How do we capture information about the world? Do our senses show
us the “real world”? - Lectures
- Anatomy of the eye and visual system in the brain
- Reception and processing
- Introduction to the scientific method
- Activities
- Case study of scientific method
- Big Questions: How does the brain make sense of sensations?
- Lectures
- Pathways and principles
- Object recognition and the role of context
- Activities
- Visual illusions
- Change blindness
- Big Questions: If the brain is the most complex material phenomenon we know, how
is it built? - Lectures
- How a working brain is built: Components and processes
- Principles: Plasticity, Darwinian processes
- Activities
- Prism goggles and vision adaptation
- Big Questions: How do our sensations relate to experience? How are humans able to
communicate and relate to others? - Lectures
- Vision and the emotional brain
- The face as an organ of communication
- Facial communication: Expression and recognition
- Activities
- Set up for intersession
- Learning materials
- Study neuroanatomy
Year 3 – Getting down to basics: transmission, integration, and response
Motivation: The fundamental driver for this year’s curriculum is the question: How does the nervous system work? Biochemical, molecular, and computational levels of explanation are unfamiliar to most monastics, but are intimately tied in to modern neuroscience. We build toward next year’s question of how brain and body work together in experience and behavior.
Curriculum
- Big Questions
- Lectures
- Introduction to Year 2
- Core concepts in neuroscience
- Dialogues on mind; Studying neuroscience
- The withdrawal (or flexor) reflex: A full neural pathway
- Activities
- Introduction of the teaching team, assign student working groups
- Re/training in use of clickers
- Worksheet: Core concepts in neuroscience
- Breakout groups / class discussion
- Reflexes, spinal cord anatomy
- Big Questions: What is the role of electricity in the nervous system? How is it produced?
- Lectures
- Electricity in the brain
- Action potentials: How neurons make electrical signals called
- Activities
- Movies of lab experiments
- Discussion
- Computer lab: Neurons in Action (from ion channels to action potentials)
- Big Questions: How do chemicals produce action in the body? Can they affect our conscious experiences?
- Lectures
- Chemical transmission
- Activities
- Manipulation of chemical neurotransmission–skin temperature
- Big Questions: How are the myriad actions of individual neurons able to produce phenomena such as a percept? Does the nervous system act like a computer?
- Lectures
- How neurons integrate synaptic inputs
- Nervous system in Tibetan medicine (Dr. Gyamtso)
- Activities
- Computer lab: From synapses to signaling
- Mid-course clicker feedback session
- Big Questions: How do our peripheral senses inform the brain? Does the brain regulate all our behaviors?
- Lectures
- Somatosensory system
- Activities
- Sense of touch: 2-point discrimination task
- Reflex modulation
- Big Questions: How does brain activity drive our movements? How does the
nervous system allow us to walk or react? Is all behavior conscious? - Lectures
- Movement and the motor systems
- Multiple motor systems in motor planning and motor control
- Activities
- Measuring electrical activity of muscles during motor tasks
- Discussion
- Big Questions: What is proprioception? How do we know where we are in space?
- Lectures
- Sensorimotor control of posture balance
- Activities
- Balance control and multisensory integration
- Sensory conflict and sensorimotor illusions
- Movement and movement disorders
- Activities
- Final exam (clickers)
- Exam results, overall scores, awards
- Closing party
Year 4 – Emotions and memory
Motivation: This year we address subjective experience, asking “Where do our feelings and thoughts come from?” and “How do we learn and remember?” We build a neuroscientific view of emotions and their actions that speak directly to monastics’ understanding of them as inherently afflictive, and discuss the neuroscience of addiction to engage Buddhist emphasis on craving as the root of affliction. Neuroscience identifies the grounds for empathy. How does this fit in to the picture?
Curriculum
- Big Questions: What are the scientific methods behind neuroscience? What role does the brain play in what we know and feel?
- Lectures
- Emotions and memory
- How do we know? Methods and logics in neuroscience
- Activities
- Introduction of the teaching team, assign student working groups
- Neuroanatomy programs
- Using brain imaging data
- Big Questions: How are emotions produced? What is the relationship of emotion and consciousness?
- Lectures
- Emotions and the brain (systems)
- Emotions and the brain: The example of fear
- Activities
- Functional neuroanatomy software
- The case of Phineas Gage
- Steps 1-5 of Day 5 memory task
- Big Questions: Are emotions inherently afflictive? What causes addiction? Can addiction be cured?
- Lectures
- Reward systems in the brain and addiction
- Afflictive emotions and drug addiction
- Nervous system in Tibetan medicine (Dr. Gyamtso)
- Depression
- Activities
- How do you recognize depression?
- Big Questions: How do we learn and remember?
- Lectures
- Introduction to memory
- Physiology of memory
- Activities
- Vocabulary quiz
- Review
- Why do emotion and memory have synergistic or conflicting effects in our
behavior? How do they help us be social? - Lectures
- Emotion and memory in action: Survival and sociality in non-human
animals - Emotion and memory in action: Survival and sociality in humans
- Emotion and memory in action: Survival and sociality in non-human
- Activities
- Short term memory: analysis of data from Day 2
- Big Questions: How is it possible to know what someone else is feeling or
thinking? Is it possible or desirable to eliminate emotions? - Lectures
- Empathy and compassion
- Activities
- Mind in the Eyes Task
- Research design: How effective are methods for cultivating empathy?
- Recap of Big Questions
- Final review, question and answer session
- Review session
- Study time
- Final exam
- Exam results, overall score, awards
- Closing party
Year 5 – Mind/Body and internal regulation
Motivation: This year we take up neuroscientific insights on issues of self regulation, relationships with the world, and the grounds of suffering and resilience, and self transformation. We further explore questions about relationships of mind/brain and body, and how they work together in relating to and managing our internal and external circumstances. These big questions are explored through examination of biorhythms, resting states, attention regulation, and stress response systems. The discovery of neuroplasticity is probed. And monastics explore how brain plasticity sets the foundation for self transformation through practices such as meditation. Students engage in activities and experiments with heart rate monitors to explore these issues.
Curriculum
- Big Questions: How does the body/brain coordinate with external conditions to both accommodate challenges or opportunities and maintain well-being?
- Lectures
- How do we know? Subject and object of inquiry in science and Buddhism
- Links between brain/mind and body
- Activities
- Introduction of the teaching team, assign student working groups
- Cell phones and introduction of mood data collection
- Big Questions: How does the body/brain accommodate rhythms in nature such as day/night or seasons?
- Lectures
- Biological rhythms
- Activities
- Heart rate monitors
- Motor memory (part 1)
- Debate: All neurons are the same (paired debate)
- Big Questions: Why do we sleep and dream? What is sleeping?
- Lectures
- Waking and sleeping
- Activities
- Motor memory (part 2)
- Guess the sleep stage
- Download heart rate monitor data; Begin analyses
- Big Questions: How does the brain juggle all the different functions that it has? Is the brain composed of specialized parts that work together like a clock?
- Lectures
- Brain networks; Resting and attention
- Exploring brain networks during meditation
- Activities
- Debate: Defend Buddhist and neuroscience views on memory (group
debate) - Analyze daily heart rate data
- Analyze heart rate data from debate
- Debate: Defend Buddhist and neuroscience views on memory (group
- Big Questions: How do brain and mind relate to ongoing bodily processes? What is stress? Is stress harmful? What is pain and where does pain come from?
- Lectures
- Meeting challenges: The stress response and health
- Affiliation and social relationships
- Activity
- Enter mood data, test hypotheses
- Big Questions: Can early experience and everyday practices change our brain and thus experiences? If so, how and how lasting are the effects?
- Lectures
- Power of context: Experience and life course development
- Effects of personal practices on the brain
- Power of practice: Meditation effects on the brain
- Activities
- Broad discussion on Buddhist ideas about concepts, self, etc.
- Meditation and heart rate
- Debate: The brain you were born with determines what you can learn and
do
- Recap of Big Questions
- Final review, question and answer session
- Review session
- Study time
- Final exam
- Exam results, overall score, awards
- Closing party
Year 6 – The mind at work / Doing science
Motivation: The final year brings it all together in understanding cognition and subjective experience. Students also participate in a thorough analytic review of the scientific process, as they design, implement and present a capstone project. The motivating questions for them are intellectual (What does neuroscience tell us about how we think and understand? How do these parallel or diverge in neuroscience or Buddhism?) and practical (What can I know through neuroscience?) Instructors work intensively with project groups at each step of the research process. Importantly, students learn the pursuit of meaningful scientific inquiry with limited resources. Lecture/discussions and projects are interwoven in successive sessions. We see all these as final steps to independent inquiry on students’ own terms.
Curriculum
- Big Questions: How do we know, in all senses? What are the logic and limits of scientific inquiry? How do science and Buddhism agree or disagree on criteria for validity?
- Lectures
- Scientific thought
- Activities
- Introduction of the teaching team, assign student working groups
- Project planning: Rubrics and work group assignments
- Debate: Planning
- Big Questions: What are concepts? Where do they come from? What is their role in thinking?
- Lectures
- Concepts: Introduction and structure
- Concepts: Function and processing
- Activities
- Projects: Introduction and methods
- Projects: Design and methods
- Lego building (memory task)
- Big Questions: How do we remember things? Is memory like a recording or
movie? What can distort memory? Can memory be improved? - Lectures
- Memory as reconstruction
- Activities
- Projects: Data collection
- Lego building (reconstruction from memory task)
- Lego memory task data analysis
- Big Questions: How do we reason and make decisions? What are the grounds for valid conclusions? What are causes of distorted reasoning?
- Lectures
- Reasoning in the world
- Reasoning: Buddhism vs. cognitive science
- Activities
- Projects: Data analysis and write-up of results
- Reasoning (IAT)
- Big Questions: Why is it that humans use language? What makes this possible? Is language related to thought? Do people with different languages think differently?
- Lectures
- Language
- Activities
- Debate planning (formulate questions, arguments)
- Paired debate: Concepts
- Write-up of debate
- Big Questions: What is the self? Are there material/neuroendocrine bases for the self? Can self be useful? Is it possible or desirable to eliminate the sense of self?
- Lectures
- The self
- Activities
- Broad discussion on Buddhist ideas about concepts, self, etc.
- Projects: Write-up of results
- Big Questions: Why is critical evaluation so important in science? Are there
similarities in Buddhist thought and practice? What are the scientific criteria for valid conclusions?
- Review session
- Study time
- Final exam
- Exam results, overall score, awards
- Closing party